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In this weeks episode of "Pushing the Limits" I interview one of the world's leading phytochemical and nutrigenomics researchers who specializes in sulforaphane.  Todays episode is all about improving cellular health, the core of health, and how activating the Nrf2 pathway through such phytonutrients like Sulforaphane (the precursors of which Glucoraphanin and Myrosinase) are found in Broccoli sprouts and other cruciferous veggies. 

You will learn:

  • How sulforaphane upregulates the Nrf2 pathway 

  • How the Nrf2 pathway acts as a master switch, turning on over 250 genes and impacting thousands of enzymes in their function. 

  • How the Nrf2 pathway upregulates the cells own intelligent endogenous antioxidant systems 

  • Why just throwing a bunch of antioxidants into the body doesn't work in quenching oxidative stress

  • The impact of upregulating Nrf2 in relation to the gut 

  • How it has system wide implications 

  • Why probiotics don't colonize the gut like you think they do

  • How probiotics (or certain strains) can still be useful in immune modulation 

  • Why you should have a food first approach

  • The traps to watch out for when buying a 'sulforaphane' supplement and why most of the ones on the market are a waste of your time and money

  • How long you should take it, typical dosing regimens, combinations with other phytonutrients and supplements.

  • How to use this information to optimize your health 

  • Why it pays to work with one of Dr Christines trained G.E.M.M protocol trained clinicians 

  • Why some people have a reaction when they start, and why that means you need it most and how to adjust the dosing while not giving up 


Dr Christine Houghton has enjoyed a fulfilling and varied career in Nutritional Medicine spanning more than 30 years — and her influential work continues to stay at the forefront of this rapidly evolving profession. As a clinician, author and educator, she is dedicated to promoting a model of health care that closely reflects the diet and lifestyle choices Mother Nature would choose herself. An individual's unique biochemistry is a significant contributor to this model.

Christine's intense appreciation of the power of food as therapy began in the 1970s, an era when there were very few supplements available. With few other choices, she soon discovered the real power of food as a potent clinical intervention tool; to this day, she adopts a 'food first' philosophy.

A decade into practice, she established a thriving multi-disciplinary practice, the Centre for Integrated Medicine near Brisbane. There, she specialized in musculoskeletal conditions, glucose-regulating disorders including type 2 diabetes and other cardio metabolic conditions, digestive health and infant and child health, especially those associated with immune dysfunction.

Passionate about the relationship between nutrients, phytochemicals and cellular defenses, Christine subsequently engaged in research at the University of Queensland, earning her a PhD in Nutritional Biochemistry-Nutrigenomics. Christine is highly-regarded internationally as an expert in the clinical application of the broccoli-derived phytochemical, Sulforaphane in human health. As founding director of Cell-Logic, she has formulated a number of nutrigenomically-active supplements which are underpinned by her doctoral research.

In addition to her scientific and other publications, Christine is the co-author of two evidence-based nutrigenomics courses: FOUNDATIONS IN NUTRIGENOMICS and ADVANCED TRANSLATIONAL NUTRIGENOMICS, both self-paced online courses for practicing clinicians and the only comprehensive courses of their kind available anywhere globally. A regular speaker at Australian and international conferences, Christine is an engaging speaker whose evidence-based presentations often challenge existing paradigms.

Personalised Health Optimisation Consulting with Lisa Tamati

Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.


Topics Lisa can help with: 

Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.

She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.

She has extensive knowledge on such therapies as hyperbaric oxygen,  intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.

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  • Basic Blood Test analysis

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  • Nutristat

  • Omega 3 to 6 status

and more 

Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine .

She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the  challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa 


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To pushing the limits,

Lisa and team

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I am getting my mojo back with regards to my health and running after treatment for breast cancer, I connected with Lisa as I was looking for positive influences from people who are long distance runners and understand our mindset. Lisa’s podcasts have been a key factor in getting me out of a negative space where I allowed others limiting beliefs to stop me from following my heart and what I believe is right for me. After 18 months of being in cancer recovery mode I wanted to get out of the cancer mindset and back to achieving goals that had been put aside. Listening to Pushing The Limits has put me onto other great podcasts, and in the process I have learnt so much and am on a pathway to a much better place with my mindset and health. Thanks so much Lisa for doing what you do and always being you.