The longevity research world is exploding right now, it's so exciting and the technology is advancing in leaps and bounds and we are able now to discover faster than ever before thanks to AI and co to test more molecules that can impact human health than ever before in the history of mankind. What would have taken years now takes weeks or months.
In this episode I talk to Michael Antonelli CEO and founder of Healthgevity. Michael is a master formulator who has spent decades in the anti-ageing and longevity space learning at the feet of many masters and who is at the forefront of working with companies at the cutting edge in peptide and bioactive ingredient development. All his formulations are science backed with clinical research and I was excited to learn about something of these novel molecules like Peptistrong, Astragin, Factor 21, NAD3, Ameal Peptide and many more.
In this episode Michael walks us through some of the cutting edge molecules, what they do and how they impact various biological pathways to hopefully improve our healthspan and lifespan.
If after listening to this episode you want to check out some of the range we now have in our shop. Click the links below:
Ignite -Metabolic health and weightloss Ignite+ is an exclusive breakthrough formula combining the leading ingredients available to increase metabolism, improve insulin signaling, body composition, reduce uptake of glucose into our bodies, and so much more. One of the best ways to prevent insulin resistance is to help remove excess glucose from our blood. We are the first to pair these several effective glucose disposal agents together to target several vital pathways that regulate metabolic efficiency.
Ignite+ is an advanced metabolic optimization formula whose ingredients have been shown to support:
Reduction of adiposity and visceral fat*
Increase thermogenesis by raising the metabolic rate and calorie burning*
Browning of white adipose tissue*
Diet-induced weight gain*
Increase fatty acid oxidation*
Ramp up ketone levels*
Improves glucose tolerance and glucose control*
Leptin and ghrelin levels*
Regulation of a healthy metabolism and mitochondrial health*
Biological aging is directly impacted by physiological integrity. Muscle strength, mass, function, quantity, and quality loss are some of the main issues associated with the process of aging. As we age the performance of our muscle cells decline which leads to a weakened immune system, sarcopenia, obesity, and chronic disease among much more. Healthgevity has selected PeptiStrong™, Senactiv® and AstraGin® which are all clinically proven ingredients to put your muscles in the best position to thrive regardless of your age.
In a recent study it was concluded that lower muscle strength in late adolescence showed direct connection with higher risk of chronic disease. As such, skeletal muscle might be the central integrator between sarcopenia, obesity, immune senescence and more in an aging biological system. Preserving muscle mass is critical for optimizing health span. Research shows the strongest one-third of the population over the age of 60 has a 50% lower death rate than the weakest, making muscle a key predictor of longevity. Recent discoveries of clinically proven 'growth promoting' ingredients have made the process of building and preserving muscle more obtainable.
PeptiStrong™, Senactiv® and AstraGin® work synergistically to target multiple mechanisms, to provide a wide range of benefits in muscle health.
Vascular health and aging are the most important health care problem in the world today. Healthy aging requires healthy arteries and a healthy heart. Cardio NAD+ is a state-of-the-art solution which uses the most novel ingredients available to help optimize cardiovascular health. As one of the most important systems in your body, we have designed this combination to be synergistic to the many different areas of cardiovascular health while demonstrating cardioprotective effects including the emerging connection between NAD+ and heart health.
Featured Supportive Benefits:
Improves net NAD+ status by supporting both its synthesis and limiting its degradation
Supports healthy blood pressure
Improves vascular aging and endothelial function
Supports healthy fibrinolytic activity and clotting function
Promotes healthy circulation and blood flow
Inhibits platelet & red blood cell aggregation
Decreases blood viscosity
Supports clinical measures of inflammation
Supports healthy blood sugar and insulin levels
Inhibits lipid peroxidation
Supports healthy lipid metabolism
Demonstrated reduction in various independent cardiovascular risk factors
Cellular senescence is a hallmark of aging, it is a permanent state of cell cycle arrest induced by cellular stresses. This has numerous implications for the body, including its ability to adapt to changes in its environment, as well as its capacity to regenerate itself. This can be beneficial for individuals to understand how cellular senescence works and what the potential benefits are for the body. Firstly, understanding cellular senescence can help us better understand aging, as this process is a major contributor to the aging process. Additionally, it can also provide insight into certain diseases and conditions that may be linked to the inability of cells to divide and proliferate properly. Finally, by targeting cellular senescence, we may be able to find new ways of fighting against aging and diseases associated with it. Thus, understanding ways to best support cellular senescence can be a powerful tool in our pursuit of longevity and improved health span. Senolytics, are small molecules that can selectively kill senescence cells and have been developed to support various age-related diseases while also extending healthspan. In recent years, emerging natural compounds have been discovered to be effective senolytic agents that are featured in this breakthrough formula. Clearance of senescent cells can support the reduction of inflammation, decrease macromolecular dysregulation, and enhance function of stem and progenitor cells.
Rejuvenate presents a unique solution for intervention through two mechanisms:
(1) eliminating senescent cells (senolytics)
(2) inhibiting of senescent- associated secretory phenotype (SASP)
Once weekly pulsed high dosing blend of senolytics which have been shown to reduce senescent cells in vivo.
Targets aging at the cellular level
Induces autophagy to promote intracellular recycling and cellular renewal
Reduce full body features of Senescence-Associated Secretory Phenotype (SASP).
Protects cells against free radicals and oxidative stress
Targets inflammaging at the cellular level and supports a healthy inflammatory response
Supports a healthy immune system
Formula designed to also treat muscle senescence.
Exercises muscles longer and harder with a boost in citrate synthase activity.
Recovers more effectively with a reduction in inflammation biomarkers.
Decreases SA-β-Gal by 63% in muscle tissue.
For more information on Michael and Healthgevity you can also go to www.healthgev.com
Throughout a career spanning over 17 years, Michael passionately devoted himself to pioneering methods aimed at enhancing longevity, optimizing healthspan, and elevating overall quality of life. His focus revolves around collaborating with leading healthcare professionals, researchers, and other likeminded healthcare leaders to create natural solutions that elevate patient outcomes.
Michael utilizes his past experiences that integrates a diverse range of therapies and services, spanning from precision diagnostics to practice management strategies, hormone optimization, nutritional supplements, and leveraging peptides. Previous roles included Chief Innovation Officer, Executive Director, and Business Development for leading companies within the healthcare industry before founding Healthgevity. His expertise extends beyond conventional approaches, emphasizing holistic well-being and personalized care as essential components to any successful medical practice.
By championing novel methodologies and innovative technologies, Michal facilitates transformative changes within the healthcare landscape, fostering advancements that positively impact both practitioners and the individuals they serve. Michael continues to remain dedicated to the pursuit of innovative strategies that enhance health and vitality while reshaping the paradigms of healthcare.
Personalised Health Optimisation Consulting with Lisa Tamati
Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.
Topics Lisa can help with:
Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.
She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.
She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.
Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine .
She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa
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Listen to the episode with Dr Minkoff here:
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