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NAD Metabolism For Longevity With Professor Joseph Baur

Ever since the book "Lifespan" came out from Dr David Sinclair, everyone and their dog and has been supplementing with nicotinamide mononucleotide and nicotinamide riboside and an effort to increase our levels in the body.NAD is essential to life. No energy production can happen without NAD. NAD Also decreases as we age so the question has always been should we and can we increase our NAD levels.

As usual in biology it's very complicated and as the science has developed we have learned many new detailed insights. 

Here is an update on the latest in that science.

In this episode of "Pushing The Limits" I have the wonderful privilege of interviewing one of the world's leading researchers in NAD metabolism, sirtuin genes and metabolic health Professor Joseph Baur.

Professor at the Perelman School of Medicine of the University of Pennsylvania,

How can you increase NAD+ levels? And do higher NAD+ levels really lead to better metabolic health? What does the research say on their benefits for Longevity.

  • We cover this critical pathway in-depth looking what the research is saying and what it currently isn't and what we have still to learn.

  • We look into mice studies and then also where the human research is at.

  • We cover the salvage pathway as well as the Preiss Handler pathway.

  • The possible role of the Microbiome and in NAD metabolism.

  • We also discussed the various NAD pools and why the mitochondria maybe a key in a NAD pool.

  • We discuss the transporter for NAD into the mitochondria that was recently discovered by Prof Baur and other labs.

  • We discuss also the possible risk factors and how we can mitigate these.

  • We look at where the research is at in relation to cancer and NAD Metabolism.

  • The role of CD 38 as a voracious consumer of in NAD and how lowering CD38 in the body may be even more beneficial than taking the precursor enzymes.

  • We discuss also why CD38 increases as we age and what we can do about it and the role of senolytics.

  • How we can increase the NAMPT enzyme so we recycle more of our NAD And whether we need to support our methylation donors when we are supplementing with the likes of NMB and NR.

If you are fascinated by longevity science and want to know how you can optimise your health moving forward then this is the episode for you!

Want to try NMN, TMG and quercetin to support your healthy NAD metabolism you can find them in my shop

 

Personalised Health Optimisation Consulting with Lisa Tamati

Lisa offers solution focused coaching sessions to help you find the right answers to your challenges.



Topics Lisa can help with: 

Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach.

She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking.

She has extensive knowledge on such therapies as hyperbaric oxygen,  intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing.

Testing Options

  • Comprehensive Thyroid testing

  • DUTCH Hormone testing

  • Adrenal Testing

  • Organic Acid Testing

  • Microbiome Testing

  • Cell Blueprint Testing

  • Epigenetics Testing

  • DNA testing

  • Basic Blood Test analysis

  • Heavy Metals 

  • Nutristat

  • Omega 3 to 6 status

and more 



Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine .

She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the  challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa 

 

Join our Patron program and support the show

Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission. 

Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two

You can join by going to  Lisa's Patron Community

Or if you just want to support Lisa with a "coffee" go to 

https://www.buymeacoffee.com/LisaT to donate $3

 

Lisa’s Anti-Aging and Longevity Supplements 

Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world. 

This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that’s what it’s in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life.

 

Subscribe to our popular Youtube channel 

with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel.

Youtube

 

Order Lisa's Books

Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge" 

Check them all out at 

https://shop.lisatamati.com/collections/books

 

Perfect Amino Supplement by Dr David Minkoff

Introducing PerfectAmino

  • PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein.

  • PerfectAmino is 3-6x the protein of other sources with almost no calories.

  • 100% vegan and non-GMO.

  • The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily.

  • Fully absorbed within 20-30 minutes!

  • No other form of protein comes close to PerfectAminos


Listen to the episode with Dr Minkoff here: 

 

Use code "tamati" at checkout to get a 10% discount on any of their devices.

 

Red Light Therapy:

Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try

Flexbeam: A wearable Red Light Device

https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38

 

Or Try Vielights’ advanced Photobiomodulation Devices

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To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to

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Enjoyed This Podcast?

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If you enjoyed tuning in, then leave us a review and share this with your family and friends.

Have any questions? You can contact my team through email (support@lisatamati.com) or find me on FacebookTwitterInstagram and YouTube.

For more episode updates, visit my website. You may also tune in on Apple Podcasts.



 To pushing the limits,

Lisa and team

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What listeners are saying


My favourite running podcast by miles⭐ ⭐ ⭐ ⭐ ⭐

This is the best podcast for long runs. Lisa is just so relatable, honest, funny and inspires me to push my own limits. Awesome guests (I particularly enjoyed the podcast with Kim Morrison) and a wide variety of topics covered. Thanks for keeping me running, Lisa!
Jinni S via Apple Podcasts · Australia · 07/02/19

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My favourite podcast ⭐ ⭐ ⭐ ⭐ ⭐

Helps me get through my boring desk job. Absolutely love this podcast. Great topics and advice that has helped me to better myself and my approach to running.
alekslikestorun 

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Two thumbs up ⭐ ⭐ ⭐ ⭐ ⭐

Always great guests, great insights and learnings that can be applied immediately for every level of experience.
JonnyHagger 

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Motivational and Inspirational ⭐ ⭐ ⭐ ⭐ ⭐

I am getting my mojo back with regards to my health and running after treatment for breast cancer, I connected with Lisa as I was looking for positive influences from people who are long distance runners and understand our mindset. Lisa’s podcasts have been a key factor in getting me out of a negative space where I allowed others limiting beliefs to stop me from following my heart and what I believe is right for me. After 18 months of being in cancer recovery mode I wanted to get out of the cancer mindset and back to achieving goals that had been put aside. Listening to Pushing The Limits has put me onto other great podcasts, and in the process I have learnt so much and am on a pathway to a much better place with my mindset and health. Thanks so much Lisa for doing what you do and always being you.
L.Faire 





 

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